How does FEMARA® work?
FEMARA® works by reducing the production of estrogen wherever it is present in the body1
FEMARA® (letrozole) is a nonsteroidal aromatase inhibitor. It inhibits the aromatase enzyme by competitively binding to the haem of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues.1
FEMARA® achieves its pharmacologic goals with a single once-daily tablet.1 To learn more about FEMARA® dosing convenience, see Dosage and Administration.
For information on the unique efficacy profile of FEMARA®, click here.
Click here for Important Safety Information for FEMARA®.
Reference: 1. FEMARA® (letrozole) [summary of product characteristics]. Basel, Switzerland: Novartis Pharma AG; 2009.











