How does FEMARA^® work?

FEMARA^® works by reducing the production of estrogen wherever it is present in the body¹

FEMARA^® (letrozole) is a nonsteroidal aromatase inhibitor. It inhibits the aromatase enzyme by competitively binding to the haem of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues.¹

FEMARA^® achieves its pharmacologic goals with a single once-daily tablet.¹ To learn more about FEMARA^® dosing convenience, see Dosage and Administration.

For information on the unique efficacy profile of FEMARA^®, click here.

Click here for Important Safety Information for FEMARA^®.

Reference: 1. FEMARA^® (letrozole) [summary of product characteristics]. Basel, Switzerland: Novartis Pharma AG; 2009.